consumption-penicillins-2015-54.html
DANMAP 2015 3D
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55 danmap 2015 5. antimicrobial
consumption
in humans inspired from initiatives performed at strama in sweden re- garding the animicrobial use in children the national campaign on use of antibiotics launched on the european awareness day in 2012 focused on viral versus bacterial infections in children. it was followed by a campaign focusing on ?red ear? (otitis media) in 2013. in 2013, following steady increases in the
consumption
of tetracyclines suspected to be related to increasing systemic treatment of acne teenagers, it was decided to further inves- tigate the possible causes behind the increase (kuhn et al, 2016). encouragingly, new data from 2014 showed a sudden unexpected decrease. this was most likely related to the raised public awareness of antibiotics as the cause of unwanted resistances in general and on the appearance of livestock- associated mrsa in humans and speculations on a possible link to the use of tetracycline in the animal husbandry (see chapter 8.5 and mrsa textbox). 5.3.6 tetracyclines for the second year in a row the
consumption
of tetracyclines decreased, though less marked, from 1.66 did to 1.61 did (3%) (figure 5.11). the decrease was observed for lymecycline and tetracycline, while doxycycline increased. since 2006 the con- sumption has altogether increased with 17% (from 1.38 did). 5.4
hospital
care 5.4.1 introduction the antimicrobial
consumption
for
hospital
care reported was related only to bed-days and
admissions
in public somatic hos- pitals. specialized
hospital
s (psychiatric
hospital
s, hospices and rehabilitation centers) were not included as they might skew the data due to contribution of a large proportion of bed-days and
admissions
but only a small proportion of antimicrobial
consumption
(approximately 3%). the
consumption
of antimi- crobial agents in
hospital
care is presented as ddd per 100 oc- cupied bed-days (dbd) and as ddd per 100
admissions
(dad) to account for
hospital
activity. data are also presented as did to enable comparison with primary health care. during the past decade, the
hospital
ization pattern in denmark has changed notably: more people are admitted to somatic
hospital
s while the average length of stay is considerably shorter (figure 5.12, table a5.4 and a5.5 in web annex). selection pressure for the emergence of antimicrobial resistance increases with increasing
hospital
activity and thus the selection pressure has increased considerably from 2006 to 2015. 5.4.2 somatic
hospital
s ? ddd per 100 occupied bed-days (dbd) in 2015, the
consumption
of antimicrobial agents in somatic
hospital
s was 103.02 dbd, a minor decrease of 1.3% from 2014 (104.30 dbd), but the first decrease in a decade follow- ing continous increases (from 67.71 dbd in 2006), (table 5.5). since 2006, the
consumption
increased with 52%. this reflects a combination of the described increased
hospital
activity and decreased number of
hospital
bed-days with an increase in ddds. in 2015 combination penicillins, for the first time since recording of the antimicrobial
consumption
was begun in 1997, represented the largest group of antimicrobials consumed fig 5.9 0 0,5 1 1,5 0 1 2 3 4 5 6 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 no.
admissions
(mill.) no. bed -days (mill.) bed-days
admissions
figure 5.12. number of bed-days and
admissions
in somatic
hospital
s, denmark danmap 2015
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