27 / 72 1 rice, a.s.c. et al. (2014), the lancet, 383(9929): 1637-1647 t he angiotensin type 2 (at2) receptor was discovered in the late 1980s when many big pharma companies researched the biology behind hypertension and the angiotensin type 1 receptor. it was quickly understood that the at2 receptor has no role in the control of blood pressure, and all marketed angiotensin receptor blockers are highly- selective at1 receptor antagonists. for a long time, the function of at2 remained unclear. but in 2004, professor maree smith from university of queensland, australia discovered that at2 receptor antagonists relieve symptoms of